The Gonal-f® RFF Redi-ject® Pen contains a manufactured version of a hormone found naturally in the body called follicle-stimulating hormone (FSH). FSH, in combination with another hormone called LH (luteinizing hormone), is responsible for the growth of eggs in the ovaries during the menstrual cycle. The Gonal-f® RFF Redi-ject® Pen is prescribed to women as a daily subcutaneous (under the skin) injection for approximately 8-12 days to help stimulate the growth and maturation of multiple eggs during fertility treatment such as IVF. It may also be prescribed to men to help improve sperm production.
The Gonal-f® RFF Redi-ject® Pen allows for dosing in 12.5 IU increments, from a minimum dose of 37.5 IU to a maximum dose of 300 IU (300 IU pen) or 450 IU (450 IU and 900 IU pens).
- Gonal-f® RFF Redi-ject Pen 300 IU
- Gonal-f® RFF Redi-ject Pen 450 IU
- Gonal-f® RFF Redi-ject Pen 900 IU
Common side effects of Gonal-f® include:
- Pain, bruising, swelling, or redness at the injection site
- Headache
- Nausea
- Ovarian cyst
- Stomach pain
- Bleeding between periods
- Pelvic Pain
- Gas
- Tiredness
- Skin problems
- Breast enlargement
- Seborrhea
Contact your doctor immediately if you experience any of the following rare but serious side effects, including:
- Severe allergic reaction: Rash, swelling of the face, lips, tongue, or throat, severe dizziness, or trouble breathing
- Lung problems: Fluid in your lungs, trouble breathing, worsening of asthma
- Blood clots: Pain, swelling or warmth in the leg, shortness of breath, chest pain
- Heart attack: Chest pain or tightness, pain that radiates up your shoulder, arm, neck, or jaw
- Stroke: Sudden problems with vision, speech, or walking, numbness on one side of your body or face
- Twisting of your ovary: Sudden onset of severe abdominal pain, nausea, vomiting
- Ectopic pregnancy: Stomach or pelvic pain (especially on one side), neck pain, nausea and vomiting, shoulder pain, rectal pain
This is not a complete list of side effects that may occur. If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor. You may report side effects to the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.
Gonal-f® RFF Redi-ject® should be stored refrigerated (36℉ to 46℉) until it is used for the first time. Should refrigeration be unavailable, the pen can be stored at room temperature (68° to 77°F) for up to 3 months. After first use, store Gonal-f® RFF Redi-ject® refrigerated or at room temperature (from 36° to 77°F) and discard after 28 days. Store your pen with the cap on in a safe place and away from light. Do not freeze your pen.
