The Lupron® 14 Day Kit (Leuprolide Acetate) is a daily subcutaneous (under the skin) injection that is prescribed to women undergoing ovarian stimulation during IVF. Lupron® belongs to a class of medications called “GnRH agonists” which work by briefly stimulating the release of FSH and LH – the hormones responsible for egg production in the ovaries. However, when Lupron® is continued for several days, it has the opposite effect of suppressing the natural production of FSH and LH. As a result, suppression with Lupron® is commonly used in IVF cycles to prevent premature ovulation (early release of eggs from the ovary) and give your fertility doctor greater control over your ovarian cycle.
Lupron® may also be used for the following:
- During ovarian stimulation cycles, as the trigger injection to induce the final maturation of the eggs prior to egg retrieval
- During IVF to help stimulate egg production in women with low ovarian reserve or who have shown a poor response to other stimulation protocols
- Treatment of endometriosis and uterine fibroids
- Treatment of advanced prostate cancer in men
The Lupron® 14 Day Kit comes with a premixed 2.8 mL multiple dose vial of Lupron®, 14 disposable syringes, and 28 alcohol wipes. Do not confuse the Lupron® 14 Day Kit with the Lupron® Trigger. While both products contain the same medication, their respective uses are very different.
- Lupron® 14mg/2.8 mL 14 Day Kit
Common side effects of Lupron® (Leuprolide Acetate) include:
- Pain, bruising, swelling, or redness at the injection site
- Hot flashes
- Sweating
- Tiredness
- Headache
- Upset stomach
- Breast changes
- Acne
- Joint/muscle aches
- Insomnia
- Decreased libido
- Vaginal dryness, discomfort, or bleeding
- Swelling of the ankles or feet
- Increased urination at night
- Dizziness
- Symptoms of a severe allergic reaction such as: swelling of the face, lips, tongue, or throat, severe dizziness, or trouble breathing
- Bone pain
- Easily broken bones
- Increased thirst or urination
- Mood changes such as depression or thoughts of suicide
- Symptoms of a heart attack such as: chest, jaw, or left arm pain, shortness of breath, or unusual sweating
- Symptoms of a stroke such as: weakness on one side of the body, slurred speech, sudden vision changes, or confusion
- Irregular heartbeat
- Severe dizziness
- Fainting
- Seizures
This is not a complete list of side effects that may occur. If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor. You may report side effects to the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.
The Lupron® 14mg/2.8 mL 14 Day Kit should be stored at room temperature (below 77℉). Do not freeze. Store in the original carton until use and protect from light.
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